On behalf of the Czech Society of Biomedical Engineering and Medical Informatics and the European Federation of Medical Informatics (EFMI) we invite you to participate at the special topic conference (STC) “Data and Knowledge for Medical Decision Support” that will be held in Prague, Czech Republic, April 17th – 19th 2013. The EFMI STC 2013 is continuing the series of successful EFMI STC conferences. It is one of the most important European events in the domains of biomedicine including health care and informatics covering information science and technology.More information is available at the web pages http://www.stc2013.org